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Jeffrey A Lieberman

Antipsychotic Trials in Schizophrenia: The CATIE Project

The approval of clozapine in the United States in 1989 by the Food and Drug Administration (FDA), and its marketing for clinical use in 1990, heralded the era of a «second-generation” of antipsychotic medications (SGAs) with «atypical” characteristics. Over the ensuing decade, five additional...